The right location is the one that makes your own trip easier.
List the places you most want to visit and how you expect to travel between them. A room that looks central on a map may still be inconvenient for your particular plans. Consider the arrival journey as well as the routes you will use each day.
Check practical details that photographs rarely answer: stairs, luggage storage, bathroom arrangements and how to enter the property. If accessibility matters to you, ask specific questions about the actual route from the street to the room.
Balance location with the kind of evening you want. Some travellers prefer to walk straight into a busy area; others value a quieter base and a planned journey. Choose according to your priorities rather than an undefined claim that a place is perfectly located.